Butamirate Citrate

Butamirate Citrate

Drug Nomenclature

Date of monograph revision: 14-Oct-1997; 23-Jun-1998; 07-Apr-2000; 01-Nov-2001; 01-Jul-2004; 05-Jul-2006
Synonyms: Abbott-36581; Butamirát-citrát; Butamirati Citras; Butamirato, citrato de; Butamyrate Citrate; HH-197
BAN: Butamirate Citrate [BANM]
USAN: Butamirate Citrate
INN: Butamirate Citrate [rINNM (en)]
INN: Citrato de butamirato [rINNM (es)]
INN: Butamirate, Citrate de [rINNM (fr)]
INN: Butamirati Citras [rINNM (la)]
INN: Бутамирата Цитрат [rINNM (ru)]
Chemical name: 2-(2-Diethylaminoethoxy)ethyl 2-phenylbutyrate dihydrogen citrate
Molecular formula: C18H29NO3,C6H8O7 =499.6
CAS: 18109-80-3 (butamirate); 18109-81-4 (butamirate citrate)
ATC code: R05DB13
Chemical Structure of Butamirate

Chemical Structure of Butamirate

Drug Profile

Butamirate citrate is a cough suppressant used in non-productive cough (Go to Cough) and stated to have a central action. The usual dose is up to 30 mg daily in 3 or 4 divided doses by mouth; some countries permit up to 90 mg daily in divided doses. Modified-release tablets containing 50 mg have been given 2 or 3 times daily.

Preparations

Single-ingredient Preparations

The symbol ¤ denotes a preparation which is discontinued or no longer actively marketed.

Argentina: Dosodos; Talasa NF; Tossec; Belgium: Quintex Pediatrique; Quintex; Sinecod; Brazil: Besedan; Czech Republic: Sinecod; Tussin; Germany: Pertix¤; Sinecod¤; Greece: Antis; Antitoss; Betavix; Boutavixal; Butacodin; Butamir; Butrin; Buvastin; Chemisolv; Chributan; Codexine-R; Codimin; Cyne¤; Devix; Drosten; Leogumil; Minatuss; Nontoss; Novamir; Oaxen; Pandigal; Pintal; Roctylan; Rondover; Safarol; Sinecod; Stilex; Velkacet; Verocod; Zestapron¤; Zetapron; Hungary: Sinecod; Italy: Butiran; Lenistar; Lexosedin; Sinecod Tosse Sedativo; Portugal: Sinecod; Russia: Sinecod (Синекод); Spain: Sinecod¤; Switzerland: DemoTussol; NeoCitran Antitussif; Sinecod; Thailand: Sinecod;

Multi-ingredient Preparations

The symbol ¤ denotes a preparation which is discontinued or no longer actively marketed.

Argentina: Muco Dosodos; Brazil: Novotussan; Czech Republic: Stoptussin; Russia: Stoptussin (Стоптуссин); Switzerland: Hicoseen;



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